Hepatosplenic alpha/beta T cell lymphoma presenting with cold agglutinin disease
نویسندگان
چکیده
منابع مشابه
Primary Gastrointestinal Diffuse Large B Cell Lymphoma Presenting with Cold Agglutinin Disease
Cold agglutinin disease (CAD) is an autoimmune hemolytic anemia (AIHA) generally caused by IgM autoantibodies which exhibit maximal reactivity at 4°C. CAD can be idiopathic or secondary to some diseases and/or conditions. Only a minority of cases of secondary AIHA in non-Hodgkin's lymphoma (NHL) are associated with cold antibodies. Diffuse large B cell lymphoma (DLBCL) is the most common subtyp...
متن کاملHepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease.
Tumour necrosis factor inhibitors have revolutionised the management of Crohn's disease, but reports of a possible association between concomitant infliximab and immunomodulator therapy and hepatosplenic T-cell lymphoma (a rare form of aggressive non-Hodgkin's lymphoma) have emerged. We describe the first case in Australia of hepatosplenic T-cell lymphoma in a patient who had been treated with ...
متن کاملHepatosplenic T cell lymphoma in inflammatory bowel disease.
OBJECTIVE This article reviews the current literature and knowledge about hepatosplenic T-cell lymphoma (HSTCL), providing an overview of the clinical features, a description of its pathology and immunophenotypic traits in relation to other lymphomas. In addition, we explore the history of reported cases of hepatosplenic T-cell lymphoma in relation to the possible existence of a causal relation...
متن کاملHepatosplenic T-cell lymphoma: A case series.
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of Non-Hodgkin Lymphoma (NHL), grouped under the mature or peripheral T-cell lymphomas. It is characterised by extranodal infiltration and proliferation of malignant T-cells within the sinusoids of the liver, sinuses and red pulp of the spleen, and the bone marrow. The tumour cells express CD2 and CD3, but are CD4, CD5 and CD8 negative and ex...
متن کاملLiterature Review : Hepatosplenic T - cell Lymphoma
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of T-cell lymphoma with poor clinical outcomes. Typical clinical features include a predominance of young male with fever, hepatosplenomegaly and cytopenia with the absence of appreciable lymphadenopathy. Diagnosis is based on examination of peripheral blood and histopathology of bone marrow, spleen or liver. In addition, immunophenotyping an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Hematology
سال: 2006
ISSN: 0939-5555,1432-0584
DOI: 10.1007/s00277-006-0212-3